P190 (MET)
\pˈiː wˈɒnhˈʌndɹədən nˈa͡ɪnti mˈɛt], \pˈiː wˈɒnhˈʌndɹədən nˈaɪnti mˈɛt], \p_ˈiː w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n n_ˈaɪ_n_t_i__ m_ˈɛ_t]\
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A cell surface protein-tyrosine kinase receptor for HEPATOCYTE GROWTH FACTOR. It consists of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and critical sites for the regulation of kinase activity. Mutations of the gene for PROTO-ONCOGENE PROTEIN C-MET are associated with papillary renal carcinoma and other neoplasia. EC 2.7.11.-.
By DataStellar Co., Ltd
