P16INK4A GENE
\pˈiː sˈɪkstiːn ˈɪŋk fˈɔːɹ ˈe͡ɪ d͡ʒˈiːn], \pˈiː sˈɪkstiːn ˈɪŋk fˈɔːɹ ˈeɪ dʒˈiːn], \p_ˈiː s_ˈɪ_k_s_t_iː_n ˈɪ_ŋ_k f_ˈɔː_ɹ ˈeɪ dʒ_ˈiː_n]\
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Tumor suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies. (From Segen, Current Med Talk, 1995) Two alternatively spliced gene products are encoded by p16: PROTEIN P16 and p14ARF PROTEIN.
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