PROTO ONCOGENE PROTEINS C ERBB 2
\pɹˈə͡ʊtə͡ʊ ˈɒnkə͡ʊd͡ʒˌiːn pɹˈə͡ʊtiːnz sˈiː ˈɜːb bˈiː tˈuː], \pɹˈəʊtəʊ ˈɒnkəʊdʒˌiːn pɹˈəʊtiːnz sˈiː ˈɜːb bˈiː tˈuː], \p_ɹ_ˈəʊ_t_əʊ ˈɒ_n_k_əʊ_dʒ_ˌiː_n p_ɹ_ˈəʊ_t_iː_n_z s_ˈiː_ ˈɜː_b b_ˈiː t_ˈuː]\
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A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR), the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members. EC 2.7.11.-.
By DataStellar Co., Ltd
Nearby Words
- proto oncogene proteins abl
- proto oncogene proteins c abl
- proto oncogene proteins c bcl 1
- proto oncogene proteins c bcl 2
- proto oncogene proteins c erba
- Proto Oncogene Proteins c erbB 2
- proto oncogene proteins c fos
- proto oncogene proteins c jun
- proto oncogene proteins c kit
- proto oncogene proteins c met
- proto oncogene proteins c mos