TUMOR SUPPRESSOR GENES
\tjˈuːmə səpɹˈɛsə d͡ʒˈiːnz], \tjˈuːmə səpɹˈɛsə dʒˈiːnz], \t_j_ˈuː_m_ə s_ə_p_ɹ_ˈɛ_s_ə dʒ_ˈiː_n_z]\
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Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.