TOPESTHESIA, TOPAESTHESIA

\tə͡ʊpsθˈiːzi͡ə], \tə‍ʊpsθˈiːzi‍ə], \t_əʊ_p_s_θ_ˈiː_z_iə]\

Definitions of TOPESTHESIA, TOPAESTHESIA

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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