SIMIAN IMMUNODEFICIENCY VIRUS
\sˈɪmi͡ən ɪmjˈuːnə͡ʊdfˌɪʃənsi vˈa͡ɪɹəs], \sˈɪmiən ɪmjˈuːnəʊdfˌɪʃənsi vˈaɪɹəs], \s_ˈɪ_m_iə_n ɪ_m_j_ˈuː_n_əʊ_d_f_ˌɪ_ʃ_ə_n_s_i v_ˈaɪ_ɹ_ə_s]\
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Species of the genus LENTIVIRUS, subgenus primate immunodeficiency viruses (IMMUNODEFICIENCY VIRUSES, PRIMATE), that induces acquired immunodeficiency syndrome in monkeys and apes (SAIDS). The genetic organization of SIV is virtually identical to HIV. SIV is 50% homologous in nucleotide sequence to HIV-1. SIV and HIV-2 exhibit close structural and immunologic properties and are 75% homologous. SIV does not cause immune deficiency in its natural host, the African green monkey, but does produce SAIDS in the rhesus macaque.
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