SELF-DEGRADATION
\sˈɛlfdɪɡɹɐdˈe͡ɪʃən], \sˈɛlfdɪɡɹɐdˈeɪʃən], \s_ˈɛ_l_f_d_ɪ_ɡ_ɹ_ɐ_d_ˈeɪ_ʃ_ə_n]\
Definitions of SELF-DEGRADATION
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.