SELF INDUCTION

\sˈɛlf ɪndˈʌkʃən], \sˈɛlf ɪndˈʌkʃən], \s_ˈɛ_l_f ɪ_n_d_ˈʌ_k_ʃ_ə_n]\
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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