ORG31338

\ˈɔːɡ θˈɜːtiwˈɒn θˈa͡ʊzənd θɹˈiːhˈʌndɹədən θˈɜːtiˈe͡ɪt], \ˈɔːɡ θˈɜːtiwˈɒn θˈa‍ʊzənd θɹˈiːhˈʌndɹədən θˈɜːtiˈe‍ɪt], \ˈɔː_ɡ θ_ˈɜː_t_i_w_ˈɒ_n θ_ˈaʊ_z_ə_n_d_ θ_ɹ_ˈiː_h_ˈʌ_n_d_ɹ_ə_d_ə_n θ_ˈɜː_t_i__ˈeɪ_t]\

Definitions of ORG31338

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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