L TYPE VDCC BETA SUBUNIT
\ˈɛl tˈa͡ɪp vˌiːdˌiːsˌiːsˈiː bˈiːtə sˈʌbjuːnˌɪt], \ˈɛl tˈaɪp vˌiːdˌiːsˌiːsˈiː bˈiːtə sˈʌbjuːnˌɪt], \ˈɛ_l t_ˈaɪ_p v_ˌiː_d_ˌiː_s_ˌiː_s_ˈiː b_ˈiː_t_ə s_ˈʌ_b_j_uː_n_ˌɪ_t]\
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Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.
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Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].