HEPATITIS B VIRUS
\hˌɛpɐtˈa͡ɪtɪs bˈiː vˈa͡ɪɹəs], \hˌɛpɐtˈaɪtɪs bˈiː vˈaɪɹəs], \h_ˌɛ_p_ɐ_t_ˈaɪ_t_ɪ_s b_ˈiː v_ˈaɪ_ɹ_ə_s]\
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The type species of the genus ORTHOHEPADNAVIRUS which causes human hepatitis B and is also apparently a causal agent in human hepatocellular carcinoma. The Dane particle is an intact hepatitis virion, named after its discoverer. Non-infectious spherical and tubular particles are also seen in the serum.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.