FIBROBLAST INTERMEDIATE FILAMENT PROTEINS

\fˈɪbɹəblˌast ˌɪntəmˈiːdi͡ət fˈɪləmənt pɹˈə͡ʊtiːnz], \fˈɪbɹəblˌast ˌɪntəmˈiːdi‍ət fˈɪləmənt pɹˈə‍ʊtiːnz], \f_ˈɪ_b_ɹ_ə_b_l_ˌa_s_t ˌɪ_n_t_ə_m_ˈiː_d_iə_t f_ˈɪ_l_ə_m_ə_n_t p_ɹ_ˈəʊ_t_iː_n_z]\

Definitions of FIBROBLAST INTERMEDIATE FILAMENT PROTEINS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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