DES ARG C5A
\dˈɛs ˈɑːɡ sˈiː fˈa͡ɪv ˈe͡ɪ], \dˈɛs ˈɑːɡ sˈiː fˈaɪv ˈeɪ], \d_ˈɛ_s ˈɑː_ɡ s_ˈiː f_ˈaɪ_v ˈeɪ]\
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Complement 5a with the carboxy-terminal arginine removed. The arginine is rapidly cleaved from the C5a fragment during complement activation by carboxypeptidase B present in normal human serum. C5a des-Arg shows complete loss of spasmogenic activity though it retains some chemotactic ability.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.