CASTRATUS
\kˈastɹatəs], \kˈastɹatəs], \k_ˈa_s_t_ɹ_a_t_ə_s]\
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One deprived of testicles. In the Southern States an animal thus situated is said to be altered. This privation has a great influence on the development of puberty. It is practised to procure a clearer and sharper voice; and in the East, the guardians of the harem, for the sake of security, are converted into Castra'ti or Eu'nuchs. Eunuchs have generally both testes and penis removed.
By Robley Dunglison
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.