AVIAN SARCOMA VIRUS TRANSFORMING PROTEIN
\ˈe͡ɪvɪən sɑːkˈə͡ʊmə vˈa͡ɪɹəs tɹansfˈɔːmɪŋ pɹˈə͡ʊtiːn], \ˈeɪvɪən sɑːkˈəʊmə vˈaɪɹəs tɹansfˈɔːmɪŋ pɹˈəʊtiːn], \ˈeɪ_v_ɪ__ə_n s_ɑː_k_ˈəʊ_m_ə v_ˈaɪ_ɹ_ə_s t_ɹ_a_n_s_f_ˈɔː_m_ɪ_ŋ p_ɹ_ˈəʊ_t_iː_n]\
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A tyrosine-specific protein kinase encoded by the v-src oncogene of Rous sarcoma virus. The transforming activity of pp60 (v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60 (v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine. EC 2.7.11.-.
By DataStellar Co., Ltd
