AVIAN NEPHROSIS VIRUSES
\ˈe͡ɪvɪən nɛfɹˈə͡ʊsɪs vˈa͡ɪɹəsɪz], \ˈeɪvɪən nɛfɹˈəʊsɪs vˈaɪɹəsɪz], \ˈeɪ_v_ɪ__ə_n n_ɛ_f_ɹ_ˈəʊ_s_ɪ_s v_ˈaɪ_ɹ_ə_s_ɪ_z]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.