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An unresolving, predominately periportal, hepatitis, usually with hypergammaglobulinemia and serum autoantibodies. The existence of subgroups (types 1, 2, and 3) based on serological findings are controversial. Additionally, some patients have variant forms, where there are features associated with both autoimmune hepatitis and another type of chronic liver disease (overlap syndromes) or where there are findings incompatible with autoimmune hepatitis (outlier syndromes). (From Czaja, Ann Intern Med. 1996; 125:588-598)